Article: Identification of a 6-cytokine prognostic signature in patients with primary glioblastoma harboring M2 microglia/macrophage phenotype relevance.
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Cai J; Zhang W; Yang P; Wang Y; Li M; Zhang C; Wang Z; Hu H; Liu Y; Li Q; Wen J; Sun B; Wang X; Jiang T; Jiang C
PLoS ONE, 2015
10.1371/journal.pone.0126022.t002
Table 2 Factors associated with OS and PFS in the Cox regression analysis for patients from the CGGA dataset.
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Univariate Cox Regression
Mutivariate Cox Regression
Variable
HR
95%CI
p value
HR
95%CI
p value
Overall Survival
Age at diagnosis <45 vs. ≥45 1.038
0.644-1.672
>0.05
Gender Male vs. Female 0.854
0.526-1.388
>0.05
Preoperative KPS score <80 vs. ≥80 4.869
2.886-8.216
<0.001 4.724
2.524-8.840
<0.001
Risk score Low vs. High 2.323
1.426-3.785
0.001 2.352
1.256-4.403
<0.01
Chemotherapy Yes vs.No 2.23
1.373-3.622
0.001 1.923
0.998-3.705
0.051
Radiotherapy Yes vs.No 1.914
1.146-3.194
<0.05 0.887
0.449-1.753
>0.05
MGMT Methy vs. Unmethy 2.088
1.175-3.710
<0.05 1.48
0.765-2.863
>0.05
IDH1/2 Mutation status MUT vs. WT 1.595
0.777-3.272
>0.05
Extent of surgery Total vs.Subtotal 1.356
0.837-2.197
>0.05
Progression-free Survival
Age at diagnosis <45 vs. ≥45 0.896
0.567-1.418
>0.05
Gender Male vs. Female 0.805
0.501-1.291
>0.05
Preoperative KPS score <80 vs. ≥80 4.514
2.722-7.487
<0.001 3.926
2.173-7.094
<0.001
Risk score Low vs. High 2.019
1.259-3.239
<0.01 1.78
1.004-3.157
<0.05
MGMT Methy vs. Unmethy 1.931
1.104-3.379
<0.05 1.415
0.762-2.629
>0.05
Chemotherapy Yes vs.No 1.974
1.229-3.169
<0.01 1.404
0.784-2.514
>0.05
Radiotherapy Yes vs.No 1.422
0.857-2.362
>0.05
IDH1/2 Mutation status MUT vs. WT 1.313
0.667-2.587
>0.05
Extent of surgery Total vs.Subtotal 1.225
0.771-1.945
>0.05
Inferred neuron-electrophysiology data values
Neuron Type
Neuron Description
Ephys Prop
Extracted Value
Standardized Value
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